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Professor Richard Hooper

Richard

Professor of Medical Statistics

Email: r.l.hooper@qmul.ac.uk
Telephone: Tel: +44 (0)20 7882 7324
Website: Twitter: @RL_Hooper

Profile

I joined QMUL in 2010 having worked previously as a biostatistician at Cambridge University, King’s College London, Imperial College London, and also for a short time with the Government Statistical Service in the Department of Health. I am Professor of Medical Statistics and Deputy Centre Lead at the Centre for Evaluation & Methods, and Lead of the Methodology Research Unit, as well as Institutional Co-Lead at QMUL for the NIHR Research Support Service (RSS) Hub at Imperial College London & Partners. In 2019 I was awarded a Senior Fellowship with The Healthcare Improvement Studies (THIS) Institute, and am now a member of their alumni community.

Research

Research Interests:

My research programme is aimed at driving innovation in the design of randomised evaluations of health interventions and quality improvement programmes, including stepped wedge trials and other novel approaches to clustered trials. To find out more about stepped wedge trials visit my Stepped Wedgehog website. My work has appeared in the BMJ, the International Journal of Epidemiology, the Journal of Clinical Epidemiology, Statistics in Medicine, and Statistical Methods in Medical Research. I have given invited talks at international conferences of the International Society for Clinical Biostatistics, Royal Statistical Society, and Society for Clinical Trials.

Publications

  • (publicationYear). Improving outcomes in adult patients who self-harm—evaluating a brief psychological intervention in emergency departments (ASSURED): protocol of a randomised controlled clinical trial. nameOfConference


  • (2025). Clinical efficacy of subsensory sacral neuromodulation in adults with faecal incontinence: The SUBSoNIC crossover randomised controlled trial and cohort follow‐up study. nameOfConference


  • Hemming K, Hall J, Copas A et al. (publicationYear). Covariate adjustment in cluster randomised trials: a practical guide. nameOfConference


  • Greenwood K, Jones CI, Yaziji N et al. (2025). Team-based motivational engagement intervention in young people with first-episode psychosis: the EYE-2 cluster RCT with economic and process evaluation.. nameOfConference


  • Watson SI, Hooper R (2025). Grand rounds in methodology: improving the design of staggered implementation cluster randomised trials. nameOfConference


  • Hemming K, Thompson JY, Hooper RL et al. (publicationYear). Guidelines for the content of statistical analysis plans in clinical trials: protocol for an extension to cluster randomized trials. nameOfConference


  • Grantham KL, Forbes AB, Hooper R et al. (2025). The relative efficiency of staircase and stepped wedge cluster randomised trial designs. nameOfConference


  • Hooper R (2025). To adjust, or not to adjust, for multiple comparisons. nameOfConference


  • McKenzie JE, Taljaard M, Hemming K et al. (publicationYear). Reporting of cluster randomised crossover trials: extension of the CONSORT 2010 statement with explanation and elaboration. nameOfConference


  • Relton C, Blake MK, Bridge G et al. (publicationYear). Place-based household vouchers for locally supplied fruit and vegetables: the Fresh Street pilot cluster randomised controlled trial. nameOfConference


View profile publication page

Supervision

  • Laeti de Abreu Nunes (Wellcome Trust PhD Programme in Science): Moving beyond frequency tables for the analysis and presentation of harm outcomes in randomised controlled trials

  • Nadine Marlin (NIHR Doctoral Fellowship): Statistical methods for modelling complex associations in meta-analysis

  • Olivier Quintin (NIHR Doctoral Fellowship): Developing guidance on the design and analysis of stepped wedge trials with small numbers of clusters
  • Yuanjin Zhang (Trials Methodology Research Partnership DTP): Statistical methods for economic evaluations alongside stepped wedge cluster randomised controlled trials

 

PhD opportunity to start October 2025:

Optimal design for the next generation of stepped wedge trials

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